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PUBLICATIONS

2022

2022

  1. Lam KHB, Leon AJ, Hui W, Lee SC, Batruch I, Faust K, Klekner A, Hutóczki G, Koritzinsky M, Richer M, Djuric U, Diamandis P. Topographic mapping of the glioblastoma proteome reveals a triple-axis model of intra-tumoral heterogeneity. Nat Commun. 2022 Jan 10;13(1):116. 

  2. Paff M, Samuel N, Alsafwani N, Paul D, Diamandis P, Climans SA, Kucharczyk W, Ding MYR, Gao AF, Lozano AM. Leukoencephalopathy with brain calcifications and cysts (Labrune syndrome) case report: diagnosis and management of a rare neurological disease. BMC Neurol. 2022 Jan 5;22(1):10

  3. Faust K, Lee MK, Dent A, Fiala C, Portante A, Rabindranath M, Alsafwani N, Gao A, Djuric U, Diamandis P. Integrating morphologic and molecular histopathological features through whole slide image registration and deep learning. Neuro-oncology advances. 2022 Jan;4(1)

  4. Melliou S, Sangster KT, Djuric U, Diamandis P. The promise of organoids for unraveling the proteomic landscape of the developing human brain. Molecular Psychiatry. 2022 Jan;27(1):73-80.

  5. Lee MK, Rabindranath M, Faust K, Yao J, Gershon A, Alsafwani N, Diamandis P. Compound computer vision workflow for efficient and automated immunohistochemical analysis of whole slide images. Journal of Clinical Pathology. 2022 Feb 14.

  6. Valkanas K, Diamandis P. Pareto distribution in virtual education: challenges and opportunities. Canadian Medical Education Journal. 2022 Mar;13(1):102.

  7. Dent A, Diamandis P. Integrating computational pathology and proteomics to address tumor heterogeneity. The Journal of Pathology. 2022 Apr 3.

  8. Nguyen HD, Diamandis P, Scott MS, Richer M. Deciphering of Adult Glioma Vulnerabilities through Expression Pattern Analysis of GABA, Glutamate and Calcium Neurotransmitter Genes. Journal of Personalized Medicine. 2022 Apr 14;12(4):633.
  9. Melliou S, Sangster KT, Kao J, Zarrei M, Lam KHB, Howe J, Papaioannou MD, Tsang QPL, Borhani OA, Sajid RS, Bonnet C, Leheup B, Shannon P, Scherer SW, Stavropoulos DJ, Djuric U, Diamandis P. Regionally defined proteomic profiles of human cerebral tissue and organoids reveal conserved molecular modules of neurodevelopment. Cell Rep. 2022 May 24;39(8):110846. doi: 10.1016/j.celrep.2022.110846. PMID: 35613588.

  10. Lam KHB, Faust K, Yin R, Fiala C, Diamandis P. The Brain Protein Atlas: A conglomerate of proteomics datasets of human neural tissue. Proteomics. 2022 Dec;22(23-24):e2200127. doi: 10.1002/pmic.202200127. Epub 2022 Aug 30. PMID: 35971647.

  11. Lam KHB, Diamandis P. Niche deconvolution of the glioblastoma proteome reveals a distinct infiltrative phenotype within the proneural transcriptomic subgroup. Sci Data. 2022 Oct 1;9(1):596. doi: 10.1038/s41597-022-01716-5. PMID: 36182941; PMCID: PMC9526702.

  12. Melliou S, Diamandis P. Generation of cell-type-specific proteomes of neurodevelopment from human cerebral organoids. STAR Protoc. 2022 Oct 21;3(4):101774. doi: 10.1016/j.xpro.2022.101774. PMID: 36313540; PMCID: PMC9597183. 

2021

2021

  1. Melliou S, Sangster KT, Djuric U, Diamandis P. The promise of organoids for unraveling the proteomic landscape of the developing human brain. Mol Psychiatry. 2021 Oct 26.

  2. Xia D, Leon AJ, Yan J, Silva A, Bakhtiari M, Tremblay-LeMay R, Selvarajah S, Sabatini P, Diamandis P, Pugh T, Kridel R, Delabie J. DNA Methylation-Based Classification of Small B-Cell Lymphomas: A Proof-of-Principle Study. J Mol
    Diagn. 2021 Dec;23(12):1774-1786

  3. Dehkharghanian T, Rahnamayan S, Riasatian A, Bidgoli AA, Kalra S, Zaveri M, Babaie M, Seyed Sajadi MS, Gonzalelz R, Diamandis P, Pantanowitz L, Huang T, Tizhoosh HR. Selection, Visualization, and Interpretation of Deep Features in
    Lung Adenocarcinoma and Squamous Cell Carcinoma. Am J Pathol. 2021 Dec;191(12):2172-2183.

  4. Riasatian A, Babaie M, Maleki D, Kalra S, Valipour M, Hemati S, Zaveri M, Safarpoor A, Shafiei S, Afshari M, Rasoolijaberi M, Sikaroudi M, Adnan M, Shah S, Choi C, Damaskinos S, Campbell CJ, Diamandis P, Pantanowitz L, Kashani H, Ghodsi A, Tizhoosh HR. Fine-Tuning and training of densenet for histopathology image representation using TCGA diagnostic slides. Med Image Anal. 2021 May;70:102032. 

  5. Tizhoosh HR, Diamandis P, Campbell CJV, Safarpoor A, Kalra S, Maleki D, Riasatian A, Babaie M. Searching Images for Consensus: Can AI Remove Observer Variability in Pathology? Am J Pathol. 2021 Oct;191(10):1702-1708.

  6. Samuel N, So E, Djuric U, Diamandis P. Consumer-grade electroencephalography devices as potential tools for early detection of brain tumors. BMC Med. 2021 Jan 22;19(1):16.

  7. Diamandis P. De-coding Group 3 medulloblastoma biology with noncoding RNA. Neuro Oncol. 2021 Apr 12;23(4):525-526.

  8. Alsafwani N, Alrjoub M, Djuric U, Gao A, Diamandis P. Tumor-Infiltrating Lymphocytes Are Enriched in Nonhypoxic Glioblastoma Niches. J Neuropathol Exp Neurol. 2021 Jan 20;80(2):202-204.

I'M AN ORIGINAL CATCHPHRASE

2020

  1. Dasgupta A, Moraes FY, Rawal S, Diamandis P, Shultz DB. Focal Leptomeningeal Disease with Perivascular Invasion in EGFR-Mutant Non-Small-Cell Lung Cancer. AJNR Am J Neuroradiol. 2020 Jul 2

  2. Malcolm J, Fiala C, Djuric U, Diamandis P. Can gliomas provide insights into promoting synaptogenesis? Mol Psychiatry. 2020 May 26

  3. Roohi A, Faust K, Djuric U, Diamandis P. Unsupervised Machine Learning in Pathology: The Next Frontier. Surg Pathol Clin. 2020 Jun;13(2):349-358.

  4. Diamandis P, Prassas I, Diamandis EP. Antibody tests for COVID-19: drawing attention to the importance of analytical specificity. Clin Chem Lab Med. 2020 Jun 25;58(7):1144-1145.

  5. Schomacher M, Jiang F, Alrjoub M, Witiw CD, Diamandis P, Fehlings MG. The posterior cervical transdural approach for retro-odontoid mass pseudotumor resection: report of three cases and discussion of the current literature. Eur Spine J. 2020 Apr 15.

  6. Selvadurai HJ, Luis E, Desai K, Lan X, Vladoiu MC, Whitley O, Galvin C, Vanner RJ, Lee L, Whetstone H, Kushida M, Nowakowski T, Diamandis P, Hawkins C, Bader G, Kriegstein A, Taylor MD, Dirks PB. Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2+ Granule Neuron Precursor. Cell Rep. 2020 Apr 14;31(2):107511.

  7. Rodrigues DC, Mufteev M, Weatheritt RJ, Djuric U, Ha KCH, Ross PJ, Wei W, Piekna A, Sartori MA, Byres L, Mok RSF, Zaslavsky K, Pasceri P, Diamandis P, Morris Q, Blencowe BJ, Ellis J. Shifts in Ribosome Engagement Impact Key Gene Sets in Neurodevelopment and Ubiquitination in Rett Syndrome. Cell Rep. 2020 Mar 24;30(12):4179-4196.e11.

  8. Kalra S, Tizhoosh HR, Shah S, Choi C, Damaskinos S, Safarpoor A, Shafiei S, Babaie M, Diamandis P, Campbell CJV, Pantanowitz L. Pan-cancer diagnostic consensus through searching archival histopathology images using artificial intelligence. NPJ Digit Med. 2020 Mar 10;3:31

  9. Grenier K, Kao J, Diamandis P. Three-dimensional modeling of human neurodegeneration: brain organoids coming of age. Mol Psychiatry. 2020. Feb;25(2):254-274.

2020

I'M AN ORIGINAL CATCHPHRASE

2019

  1. Xie Q, Faust K, Van Ommeren R, Sheikh A, Djuric U, Diamandis P. Deep learning for image analysis: Personalizing medicine closer to the point of care. Crit Rev Clin Lab Sci. 2019 Jan;56(1):61-73.

  2. Sarwar S, Dent A, Faust K, Richer M, Djuric U, Van Ommeren R, Diamandis P. International Perspectives on the Advent of Artificial Intelligence in Diagnostic Pathology. npj Digital Medicine 2019; April 28. (2):28 

  3. Papaioannou MD, Djuric U, Kao J, Karimi S, Zadeh G, Aldape K, Diamandis P. Proteomic analysis of meningiomas reveals clinically-distinct molecular patterns. Neuro Oncol. 2019;21(8):1028–1038.

  4. Faust K, Bala S, Ommeren RV, Portante A, Qawahmed RA, Djuric U, Diamandis P. Intelligent feature engineering and ontological mapping of brain tumour histomorphologies by deep learning. Nat Machine Intelligence (1): 316–32 

  5. Karimi S, Zuccato JA, Mamatjan Y, et al. The central nervous system tumor methylation classifier changes neuro-oncology practice for challenging brain tumor diagnoses and directly impacts patient care. Clin Epigenetics. 2019;11(1):185

  6. Voisin MR, Ovenden C, Tsang DS, Gupta AA, Huang A, Gao AF, Diamandis P, Almeida JP, Gentili F.  Atypical Teratoid/Rhabdoid Sellar Tumor in an Adult with a Familial History of a Germline SMARCB1 Mutation: Case Report and Review of the Literature. World Neurosurg. 2019;127:336–345

  7. Djuric U, Lam KHB, Kao J, Batruch I, Jevtic S, Papaioannou MD, Diamandis P. Defining Protein Pattern Differences Among Molecular Subtypes of Diffuse Gliomas Using Mass Spectrometry. Mol Cell Proteomics. 2019 Oct;18(10):2029-2043.

  8. Sikpa D, Fouquet JP, Lebel R, Diamandis P, Richer M, Lepage M. Automated detection and quantification of breast cancer brain metastases in an animal model using democratized machine learning tools. Sci Rep. 2019 Nov 22;9(1):17333

  9. Kalra S, Tizhoosh HR, Shah S, Choi C, Damaskinos S.  Safarpoor A, Shafiei S, Babaie M, Diamandis P, Campbell CJV, Pantanowitz P. Pan-Cancer Diagnostic Consensus Through Searching Archival Histopathology Images Using Artificial Intelligence, arXiv preprint arXiv:1911.08736, 2019

2019
2018
2018
2017

pre-2017

I'M AN ORIGINAL CATCHPHRASE

2018

  1. Faust K, Xie Q, Han D, Goyle K, Volynskaya Z, Djuric U, Diamandis P. Visualizing histopathologic deep learning classification and anomaly detection using nonlinear feature space dimensionality reduction. BMC Bioinformatics. 2018 
    May 16;19(1):173

  2. Diamandis P, Aldape K. World Health Organization 2016 Classification of Central Nervous System Tumors. Neurol Clin. 2018 Aug;36(3):439-447

 

  1. Diamandis P, Wildenhain J, Clarke ID, Sacher AG, Graham J, Bellows DS, Ling EK, Ward RJ, Jamieson LG, Tyers M & Dirks PB. Chemical genetics reveals a complex functional ground state of neural stem cells. Nat Chem Biol 2007; 3:268-73.

  2. Diamandis P, Sacher AG, Tyers M & Dirks PB. New drugs for brain tumors? Insights from chemical probing of neural stem cells. Med Hypotheses 2009; 72:683-7.

  3. Diamandis P. The cost of autonomy: Estimates from recent advances in living donor kidney transplantation. J Med Ethics 2010; 36:155-159.

  4. Diamandis P. On the origins of physicians: Darwin or Lamarckian evolution? Clin Chem Lab Med. 2010; 48:1389-92.

  5. Begcevic I, Kosanam H, Martínez-Morillo E, Dimitromanolakis A, Diamandis P, Kuzmanov U, Hazrati LN, Diamandis EP. Semiquantitative proteomic analysis of human hippocampal tissues from Alzheimer's disease and age-matched control brains. Clin Proteomics. 2013;10:5.

  6. Hazrati LN, Tartaglia MC, Diamandis P, Davis KD, Green RE, Wennberg R, Wong JC, Ezerins L, Tator CH. Absence of chronic traumatic encephalopathy in retired football players with multiple concussions and neurological symptomatology. Front Hum Neurosci. 2013; 7:222.

  7. Diamandis P, Amato D, Finkelstein J, Keith J. 79-year old man with Parkinsonism and acute spinal cord compression. Brain Pathol. 2014 ;24:101-2.

  8. Keith J, Pirouzmand F, Diamandis P, Ghorab Z. Intraoperative cytodiagnosis of progressive multifocal leucoencephalopathy. Cytopathology. 2014; 25:59-61.

  9. Thompson YY, Ramaswamy V, Diamandis P, Daniels C, Taylor MD. Posterior fossa ependymoma: current insights. Childs Nerv Syst. 2015 Oct;31(10):1699-706.

  10. Diamandis P, Ferrer-Luna R, Huang RY, Folkerth RD, Ligon AH, Wen PY, Beroukhim R, Ligon KL, Ramkissoon SH. Case Report: Next generation sequencing identifies a NAB2-STAT6 fusion in Glioblastoma. Diagn Pathol. 2016 Jan 27;11(1):13. 

  11. Bamaga AK, Riazi S, Amburgey K, Ong S, Halliday W, Diamandis P, Guerguerian AM, Dowling JJ, Yoon G. Neuromuscular conditions associated with malignant hyperthermia in paediatric patients: A 25-year retrospective study. Neuromuscul Disord. 2016 Mar;26(3):201-6.

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